2022, Supplement 3
Cardiovasc Metab Sci 2022; 33 (S3)
Understanding high blood pressure: pathophysiological advances
Cardona-Müller, David; Cardona-Muñoz, Ernesto G
ABSTRACTHigh blood pressure (HBP) has been identified as a major risk factor for cardiovascular events such as stroke and myocardial infarction. To understand the pathophysiology of high blood pressure and other diseases which affect the cardiovascular system, it is necessary to understand how they occur. Here, we discuss pathophysiological elements which lead to HBP including a discussion on arterial stiffness, as well as the biophysical and hemodynamic components which lead to the sustenance and increase in systemic blood pressure levels in adults. We also discuss humoral components which regulate blood pressure and which, when dysregulated, play a pivotal role in the pathophysiology of HBP.